Can it run on Intel Core i3 Gen 10 and 8 GB RAM with SSD storage?
No, it does not meet the recommended hardware for Genymotion Desktop. The recommended spec is an Intel Core i5 or AMD Ryzen and 16 GB RAM, while SSD is fine but not enough by itself. What are Genymotion Desktop requirements?
It may still run in some cases if the CPU supports virtualization and the OS is supported, but performance can be limited. Windows 10 is no longer officially supported, and Windows 11 is the recommended Windows version.