How can I change the file path C:\Users\william\AppData\Local\Genymobile\Genymotion\deployed\Google Nexus 4\system.vmdk to another drive in Genymotion?
Genymotion does not provide an official setting to move only the system.vmdk path to another drive.
On Windows, Genymotion’s local data is stored by default in %LOCALAPPDATA%\Genymobile, and deleting it also clears local data. Uninstall / complete cleanup instructions
If the goal is to save space on the C drive, the only options are typically to migrate the entire user configuration/local data directory or redeploy it, rather than changing this one file path. Genymotion Desktop’s installation location on Windows can be chosen during installation, but the documentation does not say that the virtual device disk file location can be changed separately. Desktop installation instructions