How to integrate using Appium Node?
Genymotion SaaS supports Appium-based automation, and there is a dedicated guide for running parallel tests with Appium on Android. See the tutorial here: Parallel tests with Appium and Genymotion SaaS.
If you want a Node.js setup, you typically point Appium to your Genymotion device via ADB and use the same desired capabilities you would use for an Android device. The integration page also lists Appium-related automation options such as Docker Android and Applitools: Integrations.